Fecal Pancreatic Elastase Stool Testing

Fecal pancreatic elastase stool testing


Pancreatic elastase is a simple, noninvasive marker in the stool for assessing for exocrine pancreatic function.  In moderate to severe cases of exocrine pancreatic insufficiency (EPI), the sensitivity of pancreatic elastase is quite high, therefore making stool elastase a good test to detect more severe cases of EPI.



  • Failure to Thrive
  • Foul Smelling, fatty stools- Steatorrhea
  • Low energy and fatigue
  • Frequent infections
  • Constipation- in rare cases


Medical Conditions- Exocrine pancreatic insufficiency can be associated with certain medical condition such as:

  • Diabetes
  • Cystic Fibrosis
  • Chronic pancreatitis
  • Autoimmune diseases and connective tissue disorders
  • Chronic inflammatory bowel disease
  • Celiac disease
  • Malabsorption and malnutrition
  • Post infectious villous atrophy


Stool Sample Collection:

Stool can be collected in a clean, dry, sterile leak proof container.  It can be kept refrigerated and returned to the lab within 24 hours of collection of the stool.  Container should be labeled with the following information: Patient’s name, Date of Birth, Time and date of collection.